Over 1 million treated with highly effective hepatitis C medicines

27 OCTOBER 2016 | GENEVA - Over one million people in low- and middle-income countries have been treated with a revolutionary new cure for hepatitis C since its introduction two years ago.

When Direct Acting Antivirals (DAAs) were first approved for hepatitis C treatment in 2013, there were widespread fears that their high price would put them out of reach for the more than 80 million people with chronic hepatitis C infections worldwide.

The new medicines have a cure rate of over 95%, fewer side effects than previously available therapies, and can completely cure the disease within three months. But at an initial estimated price of some US$85 000 they were unaffordable even in high-income countries.

Countries show hepatitis C treatment is achievable

Thanks to a series of access strategies supported by the World Health Organization (WHO) and other partners, a range of low- and middle-income countries, including Argentina, Brazil, Egypt, Georgia, Indonesia, Morocco, Nigeria, Pakistan, Philippines, Romania, Rwanda, Thailand and Ukraine – are beginning to succeed in getting drugs to people who need them. Strategies include competition from generic medicines through licensing agreements, local production and price negotiations.

"Maximizing access to lifesaving hepatitis C treatment is a priority for WHO," says Dr Gottfried Hirnschall, Director of WHO's Department of HIV and Global Hepatitis Programme. "It is encouraging to see countries starting to make important progress. However, access still remains beyond the reach for most people."

A new WHO report, Global Report on Access to Hepatitis C Treatment: Focus on Overcoming Barriers, released today shows how political will, civil society advocacy and pricing negotiations are helping address hepatitis C, a disease which kills almost 700 000 people annually and places a heavy burden on health systems’ capacities and resources.

"Licensing agreements and local production in some countries have gone a long way to make these treatments more affordable," says Dr Suzanne Hill, WHO Director for Essential Medicines and Health Products. For example, the price of a three-month treatment in Egypt dropped from US$900 in 2014 to less than US$200 in 2016.

"But there are still huge differences between what countries are paying. Some middle-income countries, which bear the largest burden of hepatitis C, are still paying very high prices. WHO is working on new pricing models for these, and other expensive medicines, in order to increase access to all essential medicines in all countries," says Dr Hill.

80% of people in need still face challenges

Among middle-income countries, the price for a three-month treatment of sofosbuvir and daclatasvir varies greatly. Costs range from US$9 400 in Brazil to US$79 900 in Romania.

High costs have led to treatment rationing in some countries, including in the European Union, where price agreements have not accounted for the full cost of treating the whole affected population.

"Today's report on access, prices, patents and registration of hepatitis C medicines will help create the much needed market transparency which should support country efforts to increase access to DAAs," said Dr Hirnschall. "We hope countries will update their hepatitis treatment guidelines, work to remove barriers to access, and make these medicines available promptly for everyone in need."

In May 2016, at the World Health Assembly, 194 countries adopted the first-ever Global Health Sector Strategy on Viral Hepatitis, agreeing to eliminate hepatitis as a public health threat by 2030. The strategy includes a target to treat 80% of people in need by this date.

Tobacco control can save billions of dollars and millions of lives

10 JANUARY 2017 | GENEVA - Policies to control tobacco use, including tobacco tax and price increases, can generate significant government revenues for health and development work, according to a new landmark global report from WHO and the National Cancer Institute of the United States of America. Such measures can also greatly reduce tobacco use and protect people’s health from the world’s leading killers, such as cancers and heart disease.

But left unchecked, the tobacco industry and the deadly impact of its products cost the world’s economies more than US$ 1 trillion annually in healthcare expenditures and lost productivity, according to findings published in The economics of tobacco and tobacco control. Currently, around 6 million people die annually as a result of tobacco use, with most living in developing countries.

The almost 700-page monograph examines existing evidence on two broad areas:

• The economics of tobacco control, including tobacco use and growing, manufacturing and trade, taxes and prices, control policies and other interventions to reduce tobacco use and its consequences; and
• The economic implications of global tobacco control efforts.

"The economic impact of tobacco on countries, and the general public, is huge, as this new report shows," says Dr Oleg Chestnov, WHO’s Assistant Director-General for Noncommunicable Diseases (NCDs) and mental health. "The tobacco industry produces and markets products that kill millions of people prematurely, rob households of finances that could have been used for food and education, and impose immense healthcare costs on families, communities and countries."

Globally, there are 1.1 billion tobacco smokers aged 15 or older, with around 80% living in low- and middle-income countries. Approximately 226 million smokers live in poverty.

The monograph, citing a 2016 study, states that annual excise revenues from cigarettes globally could increase by 47%, or US$ 140 billion, if all countries raised excise taxes by about US$ 0.80 per pack. Additionally, this tax increase would raise cigarette retail prices on average by 42%, leading to a 9% decline in smoking rates and up to 66 million fewer adult smokers.

"The research summarized in this monograph confirms that evidence-based tobacco control interventions make sense from an economic as well as a public health standpoint," says the monograph's co-editor, Distinguished Professor Frank Chaloupka, of the Department of Economics at the University of Illinois at Chicago.

The monograph’s major conclusions include:

• The global health and economic burden of tobacco use is enormous and is increasingly borne by low- and middle-income countries (LMICs). Around 80% of the world’s smokers live in LMICs.
• Effective policy and programmatic interventions exist to reduce demand for tobacco products and the death, disease, and economic costs resulting from their use, but these interventions are underused. The WHO Framework Convention on Tobacco Control (WHO FCTC) provides an evidence-based framework for government action to reduce tobacco use.
• Demand reduction policies and programmes for tobacco products are highly cost-effective. Such interventions include significant tobacco tax and price increases; bans on tobacco industry marketing activities; prominent pictorial health warning labels; smoke-free policies and population-wide tobacco cessation programmes to help people stop smoking. In 2013-2014, global tobacco excise taxes generated nearly US$ 269 billion in government revenues. Of this, less than US$ 1 billion was invested in tobacco control.
• Control of illicit trade in tobacco products is the key supply-side policy to reduce tobacco use and its health and economic consequences. In many countries, high levels of corruption, lack of commitment to addressing illicit trade, and ineffective customs and tax administration, have an equal or greater role in driving tax evasion than do product tax and pricing. The WHO FCTC Protocol to Eliminate Illicit Trade in Tobacco Products applies tools, like an international tracking and tracing system, to secure the tobacco supply chain. Experience from many countries shows illicit trade can be successfully addressed, even when tobacco taxes and prices are raised, resulting in increased tax revenues and reduced tobacco use.
• Tobacco control does not harm economies: The number of jobs dependent on tobacco has been falling in most countries, largely due to technological innovation and privatization of once state-owned manufacturing. Tobacco control measures will, therefore, have a modest impact on related employment, and not cause net job losses in the vast majority of countries. Programmes substituting tobacco for other crops offer growers alternative farming options.
• Tobacco control reduces the disproportionate health and economic burden that tobacco use imposes on the poor. Tobacco use is increasingly concentrated among the poor and other vulnerable groups.
• Progress is being made in controlling the global tobacco epidemic, but concerted efforts are needed to ensure progress is maintained or accelerated. In most regions, tobacco use prevalence is stagnant or falling. But increasing tobacco use in some regions, and the potential for increase in others, threatens to undermine global progress in tobacco control.
• The market power of tobacco companies has increased in recent years, creating new challenges for tobacco control efforts. As of 2014, 5 tobacco companies accounted for 85% of the global cigarette market. Policies aimed at limiting the market power of tobacco companies are largely untested but hold promise for reducing tobacco use.

Dr Douglas Bettcher, WHO Director for the Prevention of NCDs, says the new report gives governments a powerful tool to combat tobacco industry claims that controls on tobacco products adversely impact economies. "This report shows how lives can be saved and economies can prosper when governments implement cost-effective, proven measures, like significantly increasing taxes and prices on tobacco products, and banning tobacco marketing and smoking in public," he adds.

Tobacco control is a key component of WHO’s global response to the epidemic of NCDs, primarily cardiovascular disease, cancers, chronic obstructed pulmonary disease and diabetes. NCDs account for the deaths of around 16 million people prematurely (before their 70th birthdays) every year. Reducing tobacco use plays a major role in global efforts to achieve the Sustainable Development Goal of reducing premature deaths from NCDs by one-third by 2030.

Early cancer diagnosis saves lives, cuts treatment costs

3 FEBRUARY 2017 | GENEVA - New guidance from WHO, launched ahead of World Cancer Day (4 February), aims to improve the chances of survival for people living with cancer by ensuring that health services can focus on diagnosing and treating the disease earlier.

New WHO figures released this week indicate that each year 8.8 million people die from cancer, mostly in low- and middle-income countries. One problem is that many cancer cases are diagnosed too late. Even in countries with optimal health systems and services, many cancer cases are diagnosed at an advanced stage, when they are harder to treat successfully.

"Diagnosing cancer in late stages, and the inability to provide treatment, condemns many people to unnecessary suffering and early death," says Dr Etienne Krug, Director of WHO’s Department for the Management of Noncommunicable Diseases, Disability, Violence and Injury Prevention.

"By taking the steps to implement WHO’s new guidance, healthcare planners can improve early diagnosis of cancer and ensure prompt treatment, especially for breast, cervical, and colorectal cancers. This will result in more people surviving cancer. It will also be less expensive to treat and cure cancer patients."

All countries can take steps to improve early diagnosis of cancer, according to WHO’s new Guide to cancer early diagnosis.

The three steps to early diagnosis are:

• Improve public awareness of different cancer symptoms and encourage people to seek care when these arise.
• Invest in strengthening and equipping health services and training health workers so they can conduct accurate and timely diagnostics.
• Ensure people living with cancer can access safe and effective treatment, including pain relief, without incurring prohibitive personal or financial hardship.

Challenges are clearly greater in low- and middle-income countries, which have lower abilities to provide access to effective diagnostic services, including imaging, laboratory tests, and pathology – all key to helping detect cancers and plan treatment. Countries also currently have different capacities to refer cancer patients to the appropriate level of care.

WHO encourages these countries to prioritize basic, high-impact and low-cost cancer diagnosis and treatment services. The Organization also recommends reducing the need for people to pay for care out of their own pockets, which prevents many from seeking help in the first place.

Detecting cancer early also greatly reduces cancer’s financial impact: not only is the cost of treatment much less in cancer’s early stages, but people can also continue to work and support their families if they can access effective treatment in time. In 2010, the total annual economic cost of cancer through healthcare expenditure and loss of productivity was estimated at US$ 1.16 trillion.

Strategies to improve early diagnosis can be readily built into health systems at a low cost. In turn, effective early diagnosis can help detect cancer in patients at an earlier stage, enabling treatment that is generally more effective, less complex, and less expensive. For example, studies in high-income countries have shown that treatment for cancer patients who have been diagnosed early are 2 to 4 times less expensive compared to treating people diagnosed with cancer at more advanced stages.

Dr Oleg Chestnov, WHO Assistant Director-General for Noncommunicable Diseases and Mental Health, notes: "Accelerated government action to strengthen cancer early diagnosis is key to meet global health and development goals, including the Sustainable Development Goals (SDGs)."

SDG 3 aims to ensure healthy lives and promote well-being for all at all ages. Countries agreed to a target of reducing premature deaths from cancers and other noncommunicable diseases (NCDs) by one third by 2030. They also agreed to achieve universal health coverage, including financial risk protection, access to quality essential health-care services, and access to safe, effective, quality and affordable essential medicines and vaccines for all. At the same time, efforts to meet other SDG targets, such as improving environmental health and reducing social inequalities can also help reduce the cancer burden.

Cancer is now responsible for almost 1 in 6 deaths globally. More than 14 million people develop cancer every year, and this figure is projected to rise to over 21 million by 2030. Progress on strengthening early cancer diagnosis and providing basic treatment for all can help countries meet national targets tied to the SDGs.

Note to editors:

Most people diagnosed with cancer live in low- and middle-income countries, where two thirds of cancer deaths occur. Less than 30% of low-income countries have generally accessible diagnosis and treatment services, and referral systems for suspected cancer are often unavailable resulting in delayed and fragmented care. The situation for pathology services was even more challenging: in 2015, approximately 35% of low-income countries reported that pathology services were generally available in the public sector, compared to more than 95% of high-income countries.

Comprehensive cancer control consists of prevention, early diagnosis and screening, treatment, palliative care, and survivorship care. All should be part of strong national cancer control plans. WHO has produced comprehensive cancer control guidance to help governments develop and implement such plans to protect people from the onset of cancer and to treat those needing care.

Cancers, along with diabetes, cardiovascular and chronic lung diseases, are also known as NCDs, which were responsible for 40 million (70%) of the world’s 56 million deaths in 2015. More than 40% of the people who died from an NCD were under 70 years of age.

WHO, and the international community, have set targets to reduce such premature NCD deaths by 25% by 2025 and by one third by 2030, the latter as part of the SDGs. Countries have endorsed a range of targets to address NCDs, including making available and affordable basic medical technologies and essential drugs for treating cancers and other conditions in health facilities.

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Colours is a Filipino Magazine satellite television channel based in Makati City. It is owned and operated by MediaQuest Holdings, a wholly owned subsidiary of the PLDT Beneficial Trust Fund through TV5 Network Inc.. Its programming is composed primarily of lifestyle and reality shows

Education is the most important factor for the development of human civilization.Education provides the nation with man powers, promotes national unity and uplifts public awareness. A country needs different kinds of man powers such as doctors, engineers, teachers,

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Dawlance New Health Zone Plus Reflection 9175 WB 12 cu ft Refrigerator

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Dawlance is a Pakistani manufacture of major home appliance's based in Karachi. Founded in 1980, it was acquired by Istanbul based Arçelik in 2016

Dawlance has three factories, two sites in Karachi and one in Hyderabad, with a total of 4,000 employees.It manufacture's washing machines, freezers, split air conditioner and microwave oven's.

In 2015, Dawlance had revenues of $220.6 million selling product's in Pakistan and Middle East. Similarly, its EBITDA earnings amounted to $45 million. It has 37 branches in addition to 750-plus franchises across the country 

It was acquired by Arçelik in November 2016 for $258m, and since then function's a wholly owned brand for Arçelik.

Dawlance presents state-of-the art refrigerators with Insect Repellent Technology y, Health Light and chic glass door reflector to give you hygienic and healthy food without compromising on style

Key Features

• Health Light- Doubles the duration of food preservation.
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Specifications

Model No.

9175 WB

Capacity (L / Cu. ft.)

350 / 12.4

Dimensions (WxHxD) MM

603 x 1511 x 595 mm

Colour Available

Red with black gradient, Black, Burgundy with black gradient

9144 WB Reflection	225 / 8	490 x 1385 x 555 mm
9170 WB Reflection	320 / 11.3	603 x 1411 x 595 mm
9175 HZP	350 / 12.4	603 x 1511 x 595 mm
9188 WB HZP	425 / 15	650 x 1569 x 625 mm
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Orient DC Inverter Easy Clean 1 Ton Split AC new

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Orient DC Inverter Heat and Cool, EC Series gives you complete control of your indoor environment. Its portable front panel makes cleaning quick and easy.

 Karachi is also Pakistan's most cosmopolitan city. Located on the shores of the Arabian Sea, Karachi is a major transportation hub. The city is home to two of Pakistan's two largest seaports, the Port of Karachi and Port Bin Qasim, as well as the busiest airport in Pakistan.

Though the Karachi region has been inhabited for millennia, the city was founded as a village named Kolachi  that was established as a fortified settlement in 1729. The settlement drastically increased in importance with the arrival of British colonialists who embarked on a major works to transform the city into a major seaport, and established connections to the extensive British Indian railway network.By the time of the Partition of British India, the city was the largest in Sindh with an estimated population of 400,000.Immediately following independence of Pakistan, the city's population increased dramatically with the arrival of hundreds of thousands of Muslim refugees from IndiaThe city experienced rapid economic growth following independence, attracting migrants from throughout Pakistan and South Asia

Karachi is now Pakistan's premier industrial and financial centre. The city has a formal economy estimated to be worth $113 billion as of 2014.Karachi collects over a third of Pakistan's tax revenue,and generates approximately 20% of Pakistan's GDPApproximately 30% of Pakistani industrial output is from Karachi,while Karachi's ports handle approximately 95% of Pakistan's foreign trade.Approximately 90% of the multinational corporations operating in Pakistan are headquartered in Karachi.Up to 70% of Karachi's workforce is employed in the informal economy which is typically not included in GDP calculations.

Karachi is one of Pakistan's most secular and socially liberal cities. It is also the most linguistically, ethnically, and religiously diverse city in Pakistan No census has been conducted in Pakistan since 1998, but with an estimated population of between 15 and 23.5 million people in its greater metropolitan region,Karachi is considered to be the second-largest city in the Muslim world, and is the world's 7th most populous urban agglomeration.Karachi is considered to be one of the world's fastest growing cities,and has communities representing almost every ethnic group in Pakistan. Karachi is also home over 1 million Bangladeshi migrants, 1 million Afghans, and up to 400,000 Rohingyas from Myanmar

Known as the "City of Lights" in the 1960s and 1970s for its vibrant nightlife,^[41 Karachi was beset by sharp ethnic, sectarian, and political conflict in the 1980s with the arrival of weaponry from the War in Afghanistan.The city had become well known for its high rates of violent crime, but recorded crimes sharply decreased following a controversial crackdown operation against criminals, the,Islamist militants initiated in 2013 by the Pakistan Rangers.The city's murder rate in 2015 had decreased by 75% compared to 2013, and kidnappings decreased by 90%, with the improved security environment triggering sharp increases in real-estate prices.

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Specifications

Cooling - Rated Capacity

3500 (1500-3900) W

Cooling - Rated Power Consumption

1100 (420-1560) W

Cooling - Running Current

4.8 (2.0-6.8) A

SEER - Cooling

3.6

Heating - Rated Capacity

3500 (1600-4000) W

Heating - Rated Power Consumption

1050 (430-1600) W

Heating - Running Current

4.6 (1.9-7.0) A

SEER - Heating

3.6

Low Voltage Operation

Yes

Samsung Galaxy J1 mini prime

Name:Samsung Galaxy J1 mini prime                         Price:18000

Samsung built integrated small model of Galaxy J1 built-intention to be named as built-ini prime. This telephone is duplicate of its elder brother and it quickly builting to hit the built-in of built integrated shops all throughout the Pakistani market. the size and specifications of Samsung Galaxy J1 builtini top exhibits that this cellphone is builtintegrated made for middle elegance peoples that cannot excessive-quit smartphones. The Korean emblem is now workbuiltintegrated difficult to provide the Samsung's Galaxy J1 Mbuilt-ini high with four.0 built-inch TFT capacitive screen with 256K coloration assist. Now watch motion pictures and movies with better pixel decision of 480 x 800 pixels. Samsung Galaxy J1's android OS is pretty energetic integrated makintegratedg the display more higher via builting integrated touch wiz built integrated may also issues and wallpapers to beautify the house display screen of Galaxy J1 Mbuilt-ini prime through Samsung. The strength sector looks sturdy with the integrated of Spreadtrum SC9830 chipset built-in quad center processor is tick integrated g with the moderate speed of one.2 GHz even as cortex A7 lessen the electricity built-in of Samsung J1 Mbuilt-ini prime to the built-inmbuiltintegrated. For better image show and superior gamintegratedg built-in Mali-400MP2 GPU works perfectly with the built integrated processor that still also enables to improve the pixel exceptional of Samsung Galaxy's J1 Mintegratedi high. For multi-taskintegratedg 1 GB of RAM is built-ing integrated its offer built integrated at the same time as for the storage reason eight GB of  garage is likewise to be had. you could also extendintegrated the reminiscence of Galaxy J1 Mbuilt-ini high up to 256 GB the assist of micro SD card. 5 MP extremely-responsive digital camera is placed on the returned that provide you with perfect image end result with only a simple click on even as on the front of J1 Mintegratedi top VGA digital camera is hooked upintegrated which is likewise really worth to say.

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Display Size	640 x 1136 pixels, 4 inches Corning Gorilla Glass, oleophobic coatingSensors: Accelerometer, gyro, proximity, compass
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Operating  Frequency / Band	GSM 850 / 900 / 1800 / 1900
3G Band	HSDPA 850 / 900 / 1700 / 1900 / 2100
4G Band	LTE
Browser	HTML (Safari)
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Entertainment	Audio/video player and editor, 3.5mm audio jack, TV-out, Twitter and Facebook integration, iCloud cloud service, Image editor, Games (built-in + downloadable)
Camera	8MP, 3264x2448 pixels, autofocus, dual-LED (True Tone) flash, geo-tagging, 1.5 µm pixel size, simultaneous HD video & image recording, touch focus, face detection, panorama, HDR, Video (1080p 30fps, 720p@120fps), light, video stabilization, 2ndary (1.2 MP, 720p@30fps, face detection, FaceTime over Wi-Fi or Cellular)
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Samsung Galaxy A5 2017

Samsung Galaxy A5 2017 

Samsung Galaxy A5 2017's retail cost in Pakistan is Rs. 47,000. Official merchants and guarantee suppliers direct the retail cost of Samsung versatile items in authority guarantee.

Retail Price of Samsung Galaxy A5 2017 in Pakistan is Rs. 47,000.

Retail Price of Samsung in USD is $451.

Samsung Galaxy A5 2017 - Inexpensive Flagship Smartphone!

Samsung delivering beat gadgets and Galaxy A5 successor is revealed that is 2017 model of this gadget. Time did not stop and this Korean mammoth is very much aware of this reality. that why they have chosen to dispatch upgraded show named Samsung Galaxy A5 2017. Same thing occur with world patterns that is the reason prestigious brands need to alter themselves as indicated by the changing wonders and winning patterns. Samsung's Galaxy A5 2017 has expanded profitability and enhanced in numerous different qualities. As a matter of first importance lets investigate the outline of gadget. 5.2" touch screen of Galaxy A5 2017 by Samsung packs super AMOLED show is with the support of 16M hues and 1080 x 1920 pixel determination to give superior quality picture quality is ideal for watching motion pictures. Samsung Galaxy A5's Exynos 7880 Octa conveys Octa center processor that time at 1.9 GHz Cortex-A53. 3 GB of RAM gives the last touch to improve the framework execution in doing multi-entrusting. Samsung A5 2017 is running android OS v6.0.1 marshmallow while the implicit memory introduced inside the savvy is 32 GB. So far every one of the specs of this model is not the same as its ancestor. Cosmic system A5 2017 conveys another camera experience to its clients, now its camera will be stronger from its past model while textual style camera will likewise be more responsive in catching selfies. A5 2017 is accompanying double SIM card coats that will permit you to exploit double system in the meantime. In the event that we investigate the network of Samsung Galaxy's A5 2017 then it bolster both 3G and 4G LTE web while Bluetooth, WI-Fi, and USB port is additionally there to interface you with external world